ADC Selects Onco360 as Partner for Zynlonta

April 28, 2021

ADC Selects Onco360 as Partner for Zynlonta

ZYNLONTA™ (loncastuximab tesirine-lpyl) Now Approved for the Treatment of Adult Patients with Relapsed/Refractory Large B Cell Lymphoma After Two or More Lines of Systemic Therapy

Louisville, Ky. – April 26, 2021 – Onco360®, the nation’s largest independent Oncology Pharmacy, has been selected by ADC Therapeutics to be the exclsuive specialty pharmacy partner for ZYNLONTA™ (loncastuximab tesirine-lpyl), a new intravenous therapy option for the treatment of adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, DLBCL arising from low grade lymphoma, and high grade B-cell lymphoma.

“Onco360 is excited to be selected as a specialty pharmacy provider for ZYNLONTA™ patients,” said Benito Fernandez, Chief Commercial Officer, Onco360. “The recent approval of ZYNLONTA™ provides a new therapy option for heavily pre-treated DLBCL patients who have failed prior lines of therapy. As a provider of this key treatment, Onco360 will support the highly specialized needs of relapsed/refractory DLBCL patients and their physicians across the US.”

According to the National Cancer Institute‘s (NCI) Surveillance, Epidemiology, and End Results (SEER) Program, approximately 81,560 patients will be diagnosed with Non-Hodgkin Lymphoma (NHL) in 2021 with a corresponding 20,720 deaths. According to the National Comprehensive Cancer Network (NCCN) Guidelines, DLBCL is the common type of NHL, representing approximately 32% of all NHL cases annually. According to NCI SEER data, DLBCL has a five-year overall survival (OS) of 63.9% when considering all stages of the disease. Based on data from various clinical trials, up to 30% of DLBCL patients will experience disease relapse, necessitating subsequent lines of therapy.


ZYNLONTA™ is manufactured by ADC Therapeutics, a commercial-stage biotechnology company that strives to improve the lives of cancer patients with its next-generation, targeted antibody-drug conjugates (ADCs). The FDA’s approval of ZYNLONTA™ comes as a result of the Phase II LOTIS-2 (NCT03589469) clinical trial which demonstrated a 48.3% overall response rate (ORR) for relapsed/refractory DLBCL patients who failed at least two prior systemic therapies who were treated with ZYNLONTA™. For full prescribing information, visit ZYNLONTA.com.

To order ZYNLONTA™, visit Onco360.com/Order


Benito Fernandez, Chief Commercial Officer
[email protected]



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